Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency
N Freitag, I Tirado-Gonzalez, G Barrientos… - Cell Death & …, 2020 - nature.com
Fetal growth restriction (FGR) is the most common pregnancy complication in developed
countries. Pregnancies affected by FGR, frequently concur with complications and high risk
of neonatal morbidity and mortality. To date, no approved treatment is available for pregnant
women affected with FGR. The objective of this study was to investigate the contribution of
galectin-3 (gal-3), a β-galactoside binding protein involved in pregnancy, placental function
and fetal growth. We demonstrated that lack of gal-3 during mouse pregnancy leads to …
countries. Pregnancies affected by FGR, frequently concur with complications and high risk
of neonatal morbidity and mortality. To date, no approved treatment is available for pregnant
women affected with FGR. The objective of this study was to investigate the contribution of
galectin-3 (gal-3), a β-galactoside binding protein involved in pregnancy, placental function
and fetal growth. We demonstrated that lack of gal-3 during mouse pregnancy leads to …
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