Generation of monoclonal antibodies specific for ORF68 of koi herpesvirus
T Aoki, T Takano, S Unajak, M Takagi, YR Kim… - … and infectious diseases, 2011 - Elsevier
Outbreaks of koi herpesvirus (KHV) infection in carp are still a serious problem worldwide.
KHV is closely related to other two cyprinid herpesviruses, pox herpesvirus (CHV) and
haematopoietic necrosis herpesvirus (CyHV-2) in goldfish. In this study, two major KHV
antigenic proteins (ORF62 and ORF68) were identified by immunoscreening using a KHV-
specific polyclonal antibody, and then monoclonal antibodies were generated for
immunodiagnostic studies. After screening hybridoma cells, one mAb against ORF68 (mAb …
KHV is closely related to other two cyprinid herpesviruses, pox herpesvirus (CHV) and
haematopoietic necrosis herpesvirus (CyHV-2) in goldfish. In this study, two major KHV
antigenic proteins (ORF62 and ORF68) were identified by immunoscreening using a KHV-
specific polyclonal antibody, and then monoclonal antibodies were generated for
immunodiagnostic studies. After screening hybridoma cells, one mAb against ORF68 (mAb …
以上显示的是最相近的搜索结果。 查看全部搜索结果