Generation of neurons and astrocytes from isolated cells of adult mammalian central
nervous system | CiNii Research … Generation of neurons and astrocytes from isolated
cells of adult mammalian central nervous system …

Neurogenesis in the mammalian central nervous system is believed to end in the period just
after birth; in the mouse striatum no new neurons are produced after the first few days after
birth. In this study, cells isolated from the striatum of the adult mouse brain were induced to
proliferate in vitro by epidermal growth factor. The proliferating cells initially expressed
nestin, an intermediate filament found in neuroepithelial stem cells, and subsequently
developed the morphology and antigenic properties of neurons and astrocytes. Newly …