Peroxidase (TPO) gene can lead to thyroid dysfunction in the population. We aimed to study
the association between genetic defects in TPO gene and patients with hypothyroidism
found in adult age. Two hundred consecutive treatment naive hypothyroid patients (age≥
18 years)(cases) who were negative for anti TPO antibody and their corresponding sex and
age matched two hundred normal individuals (controls) were enrolled. The 17 exonic …