Genetic risk variants for metabolic traits in Arab populations
Despite a high prevalence of metabolic trait related diseases in Arabian Peninsula, there is
a lack of convincingly identified genetic determinants for metabolic traits in this population.
Arab populations are underrepresented in global genome-wide association studies. We
genotyped 1965 unrelated Arab individuals from Kuwait using Cardio-MetaboChip, and
tested SNP associations with 13 metabolic traits. Models based on recessive mode of
inheritance identified Chr15: 40531386-rs12440118/ZNF106/W-> R as a risk variant …
a lack of convincingly identified genetic determinants for metabolic traits in this population.
Arab populations are underrepresented in global genome-wide association studies. We
genotyped 1965 unrelated Arab individuals from Kuwait using Cardio-MetaboChip, and
tested SNP associations with 13 metabolic traits. Models based on recessive mode of
inheritance identified Chr15: 40531386-rs12440118/ZNF106/W-> R as a risk variant …
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