Genetics of Parkinson's disease

C Klein, A Westenberger - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
genetic research in Parkinson’s disease (PD) have led to the identification of several monogenic
forms of the disorder and of numerous genetic … of the molecular genetics of PD. In brief, …

Genetics of Parkinson's disease

CM Lill - Molecular and cellular probes, 2016 - Elsevier
… gene in Parkinson's disease (PD) and the subsequent understanding that genetic factors …
, our knowledge of the genetic architecture underlying this disease has vastly improved. …

Genetics of Parkinson's disease

RL Nussbaum… - Human Molecular Genetics, 1997 - academic.oup.com
… of genes encoding drug metabolizing enzymes; (iii) whole genome scans to locate and
identify the genes … of the genetic aspects of Parkinson's disease have been published (11,12). …

Genetics of Parkinson's disease

A Cherian, KP Divya - Acta Neurologica Belgica, 2020 - Springer
… Less than a quarter century after the discovery of SNCA as the first attributable gene in
Parkinson's disease (PD), our knowledge of the genetic architecture underlying this disease has …

The genetics of Parkinson disease

H Deng, P Wang, J Jankovic - Ageing research reviews, 2018 - Elsevier
… , and genetic understanding of genetic forms of PD. We also discuss advances in screening
for genetic PD-related risk factors and how they impact geneticdisease-modifying therapies. …

Recent advances in the genetics of Parkinson's disease

I Martin, VL Dawson, TM Dawson - … and human genetics, 2011 - annualreviews.org
genetic and sporadic causes of Parkinson's disease (PD). A key feature of both sporadic and
genetic … Mutations in the autosomal recessive genes PINK1, parkin, and DJ-1 may directly …

Genetics of Parkinson's disease

T Gasser - Journal of neurology, 2001 - Springer
Over the past few years, several genes for monogenically inherited forms of Parkinson's
disease (PD) have been mapped and/or cloned. In a small number of families with autosomal …

Update on the genetics of Parkinson's disease

T Gasser - Movement disorders: official journal of the …, 2007 - Wiley Online Library
Over the last few years, several genes for monogenic forms of Parkinson's disease (PD) have
been mapped and/or cloned. Mutations have been identified in the gene for α‐synuclein in …

Genetics of Parkinson's disease–state of the art, 2013

V Bonifati - Parkinsonism & related disorders, 2014 - Elsevier
… In the past 15 years there has been substantial progress in our understanding of the genetics
of Parkinson’s disease (PD). Highly-penetrant mutations in different genes (SNCA, LRRK2, …

Genetics of Parkinson's disease

T Gasser - Clinical genetics, 1998 - Wiley Online Library
A genetic contribution to the etiology of Parkinson's disease (PD) is now well established,
based on the demonstration of a familial aggregation of the disease as demonstrated by …