Background and objectives: Extended-spectrum β-lactamase (ESBL)-producing Klebsiella
pneumoniae is a serious public health issue globally. In this study, the antibiotic resistance
genes, virulence factors, mobile genetic elements, and genetic lineages of circulating ESBL-
producing K. pneumoniae strains isolated from pigs and humans in Cameroonian abattoirs
were investigated using whole genome sequencing (WGS), in order to ascertain zoonotic
transmission (viz. from animals to humans and/or vice-versa) in the food chain. Methods …

Extended spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae remain a critical
clinical concern worldwide. The aim of this study was to characterize ESBL-producing K.
pneumoniae detected within and between two hospitals in uMgungundlovu district, South
Africa, using whole genome sequencing (WGS). An observational period prevalence study
on antibiotic-resistant ESKAPE (ie Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp.) …