… is Genomic Control (GC). In this communication we clarify how and when to use GC. We
also describe a refined approach to GC, which should be used when GC is applied to extreme …

… In this review, we summarize cases of genomic convergence in these taxa to examine
the extent and type of genomic convergence during the process of adaptation to extreme …

… to the case-control status so that case-control status could not … sequences with SNPs in the
genome vary widely in their ease of … Our initial results showed some extreme associations that …

… the discrepancy in power becomes more extreme. When population substructure is present,
… We also explore general issues of power and implementation of GC within the case-control …

… of this fly can be expected to offer insights into genomic processes and genome evolution …
are unique genomic adaptations to cope with extreme environments. The genome we present …

… a genome-wide association study in 1,621 hypertensive cases and 1,699 controls and
follow-up validation analyses in 19,845 cases and 16,541 controls using an extreme case-control …

… Genomic control (GC) can be used to correct χ 2 test statistics which are presumed to be …
We assess the behavior of GC methods in imbalanced case‐control studies using simulation. …

… The bias in a case–control study with a rare Mendelian disease. We simulated a extreme
case of population substructure: only two subpopulations and Fst=0.01. (Top) The distribution …

… We identified two new genomic loci associated with paediatric obesity on chromosomes
1q43–q44 and 8p23.1 by a meta-analysis of two GWAS for early onset extreme obesity with a …

… an extreme truncate design in any disease. We have identified two new BMD loci at genome-wide
… Our study also provides strong support that the use of extreme truncate selection is an …