Giardia duodenalisAssemblage-Specific Induction of Apoptosis and Tight Junction Disruption in Human Intestinal Epithelial Cells: Effects of Mixed Infections
WH Koh, T Geurden, T Paget… - The Journal of …, 2013 - meridian.allenpress.com
In view of the interest in genotype-specific pathogenesis in Giardia duodenalis, the aim of
the present study was to examine the effects of infection with different, or mixed, G.
duodenalis assemblages on the integrity of human intestinal epithelia. To that end, human
epithelial cells (HCT-8) were cultured and exposed to different G. duodenalis assemblages
(A, B, and E) or a combination of these assemblages. Epithelial disruption and apoptosis
were evaluated by fluorescent microscopy and apoptotic oligonucleosome quantification …
the present study was to examine the effects of infection with different, or mixed, G.
duodenalis assemblages on the integrity of human intestinal epithelia. To that end, human
epithelial cells (HCT-8) were cultured and exposed to different G. duodenalis assemblages
(A, B, and E) or a combination of these assemblages. Epithelial disruption and apoptosis
were evaluated by fluorescent microscopy and apoptotic oligonucleosome quantification …
Giardia duodenalis assemblage-specific induction of apoptosis and tight junction disruption in human intestinal epithelial cells: effects of mixed infections.
KWH Koh WanHon, T Geurden, T Paget, R O'Handley… - 2013 - cabidigitallibrary.org
In view of the interest in genotype-specific pathogenesis in Giardia duodenalis, the aim of
the present study was to examine the effects of infection with different, or mixed, G.
duodenalis assemblages on the integrity of human intestinal epithelia. To that end, human
epithelial cells (HCT-8) were cultured and exposed to different G. duodenalis assemblages
(A, B, and E) or a combination of these assemblages. Epithelial disruption and apoptosis
were evaluated by fluorescent microscopy and apoptotic oligonucleosome quantification …
the present study was to examine the effects of infection with different, or mixed, G.
duodenalis assemblages on the integrity of human intestinal epithelia. To that end, human
epithelial cells (HCT-8) were cultured and exposed to different G. duodenalis assemblages
(A, B, and E) or a combination of these assemblages. Epithelial disruption and apoptosis
were evaluated by fluorescent microscopy and apoptotic oligonucleosome quantification …
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