Gold nanoparticles modified screen-printed immunosensor for cancer biomarker HER2 determination based on anti HER2 bioconjugates
YW Hartati, D Nurdjanah, S Wyantuti… - AIP Conference …, 2018 - pubs.aip.org
Human epidermal growth factor receptor 2 (HER2) is a biomarker of breast cancer plays a
major role in the proliferation of breast cancer cells. The determination of HER2
concentration is one of the ways of early detection of breast cancer. In this study we have
developed a label free immunosensor for the detection of HER2 using an anti HER2-gold
nanoparticles (GNP) bioconjugates. Anti HER2-GNP bioconjugates synthesized by adding
anti HER2 on the GNPs that already reacted with APTMS and PEG-NHS-Maleimide. GNP …
major role in the proliferation of breast cancer cells. The determination of HER2
concentration is one of the ways of early detection of breast cancer. In this study we have
developed a label free immunosensor for the detection of HER2 using an anti HER2-gold
nanoparticles (GNP) bioconjugates. Anti HER2-GNP bioconjugates synthesized by adding
anti HER2 on the GNPs that already reacted with APTMS and PEG-NHS-Maleimide. GNP …