The interest of the educational community in the laboratory-(lab) based education has grown steadily. As remote labs have started to be a reliable alternative to traditional hands-on labs, security and safety issues are becoming increasingly important, as their interconnected nature raises new and challenging issues. The complexity increases when multiple institutions are involved in a federated lab infrastructure. This paper provides a guideline for assessing safety and security in federated labs following the VDI/VDE 2182 guideline and verifies the concept based on remote labs in three different academic institutions.