HIV genome-wide protein associations: a review of 30 years of research

G Li, E De Clercq - Microbiology and Molecular Biology Reviews, 2016 - Am Soc Microbiol
The HIV genome encodes a small number of viral proteins (ie, 16), invariably establishing
cooperative associations among HIV proteins and between HIV and host proteins, to invade
host cells and hijack their internal machineries. As a known example, the HIV envelope
glycoprotein GP120 is closely associated with GP41 for viral entry. From a genome-wide
perspective, a hypothesis can be worked out to determine whether 16 HIV proteins could
develop 120 possible pairwise associations either by physical interactions or by functional …

[PDF][PDF] HIV genome-wide protein associations: a review

G Li, E De Clercq - 2016 - researchgate.net
The HIV genome encodes a small number of viral proteins (ie, 16), invariably establishing
cooperative associations among HIV proteins and between HIV and host proteins, to invade
host cells and hijack their internal machineries. As a known example, the HIV envelope
glycoprotein GP120 is closely associated with GP41 for viral entry. From a genome-wide
perspective, a hypothesis can be worked out to determine whether 16 HIV proteins could
develop 120 possible pairwise associations either by physical interactions or by functional …
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