HLA-E polymorphisms in an Afro-descendant Southern Brazilian population
LC dos Santos, LV Tureck, PF Wowk, SB Mattar… - Human Immunology, 2013 - Elsevier
HLA-E is a non-classical I (Ib) gene which has limited polymorphism and low levels of tissue
expression. Currently, 11 alleles are described in the literature with only three protein
products. In the present study we investigated HLA-E gene variations at exons 2 and 3 and
calculated allele, genotype and haplotype frequencies in a sample of 152 individuals who
reported themselves as being Afro-descendants and who are voluntary bone marrow donors
living in the state of Paraná, Brazil. The most frequent allele in the sample analyzed was the …
expression. Currently, 11 alleles are described in the literature with only three protein
products. In the present study we investigated HLA-E gene variations at exons 2 and 3 and
calculated allele, genotype and haplotype frequencies in a sample of 152 individuals who
reported themselves as being Afro-descendants and who are voluntary bone marrow donors
living in the state of Paraná, Brazil. The most frequent allele in the sample analyzed was the …
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