Hair growth-promoting effect of Aconiti Ciliare Tuber extract mediated by the activation of Wnt/β-catenin signaling
PJ Park, BS Moon, SH Lee, SN Kim, AR Kim, HJ Kim… - Life Sciences, 2012 - Elsevier
AIMS: The activation of Wnt/β-catenin signaling pathway plays an important role in hair
follicle morphogenesis by stimulating bulge stem cells. This study was to obtain the activator
of Wnt/β-catenin signaling pathway from natural products and to determine whether this
activator can induce anagen hair growth in mice. MAIN METHODS: To identify materials that
activate Wnt/β-catenin signaling pathway, 800 natural product extracts were screened using
pTOPFlash assay and neural progenitor cell (NPC) differentiation assay. A selected extract …
follicle morphogenesis by stimulating bulge stem cells. This study was to obtain the activator
of Wnt/β-catenin signaling pathway from natural products and to determine whether this
activator can induce anagen hair growth in mice. MAIN METHODS: To identify materials that
activate Wnt/β-catenin signaling pathway, 800 natural product extracts were screened using
pTOPFlash assay and neural progenitor cell (NPC) differentiation assay. A selected extract …
Hair growth-promoting effect of Aconiti ciliare tuber extract mediated by the activation of Wnt/β-catenin signaling.
PPJ Park PhilJune, MBS Moon ByoungSan… - 2012 - cabidigitallibrary.org
Abstract Aims: The activation of Wnt/β-catenin signaling pathway plays an important role in
hair follicle morphogenesis by stimulating bulge stem cells. This study was to obtain the
activator of Wnt/β-catenin signaling pathway from natural products and to determine whether
this activator can induce anagen hair growth in mice. Main methods: To identify materials
that activate Wnt/β-catenin signaling pathway, 800 natural product extracts were screened
using pTOPFlash assay and neural progenitor cell (NPC) differentiation assay. A selected …
hair follicle morphogenesis by stimulating bulge stem cells. This study was to obtain the
activator of Wnt/β-catenin signaling pathway from natural products and to determine whether
this activator can induce anagen hair growth in mice. Main methods: To identify materials
that activate Wnt/β-catenin signaling pathway, 800 natural product extracts were screened
using pTOPFlash assay and neural progenitor cell (NPC) differentiation assay. A selected …
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