The study examined the correlation between herbal users’ beliefs and the ef cacy of herbal medicine based on health information. The study was anchored on the Health Belief Model which predicts health behaviours by focusing on the attitudes and beliefs of individuals. Using survey design, the study was carried out in select towns of Awka, Onitsha and Nnewi which represent three senatorial zones in Anambra State, Nigeria. The sample size of 400 respondents was randomly selected. The questionnaire was the instrument for data collection. Major ndings revealed that users’ beliefs do not necessarily add to the potency of herbal drugs. It also revealed that interpersonal communication is most effective through testimonials/referrals by users. Social media is equally effective for an online audience but there is minimal use of mainstream media. Based on the ndings, it is recommended that health education and health information should be emphasised. Equally, regulatory bodies in Nigeria