uniquely associated with distinctive patterns of impairment in the components of health-
related quality of life (HRQL) and how this compares with the impairment seen in common
medical disorders. Design.—Survey. Setting.—Four primary care clinics. Subjects.—A total
of 1000 adult patients (369 selected by convenience and 631 selected by site-specific
methods to avoid sampling bias) assessed by 31 primary care physicians using PRIME-MD …