Heart on a chip: micro-nanofabrication and microfluidics steering the future of cardiac tissue engineering

M Kitsara, D Kontziampasis, O Agbulut… - Microelectronic …, 2019 - Elsevier
The evolution of micro and nanofabrication approaches significantly spurred the
advancements of cardiac tissue engineering over the last decades. Engineering in the micro
and nanoscale allows for the rebuilding of heart tissues using cardiomyocytes. The
breakthrough of human induced pluripotent stem cells expanded this field rendering the
development of human tissues from adult cells possible, thus avoiding the ethical issues of
the usage of embryonic stem cells but also creating patient-specific human engineered …
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