that hepatic injury occurs in a significant proportion of patients, particularly in those with
severe or critical illness. Mild increase in sinusoidal lymphocytic infiltration, sinusoidal
dilatation, steatosis and multifocal hepatic necrosis are the pathologic changes reported.
Direct viral‐induced cellular injuries and potential hepatotoxicity from therapeutic drugs are
two likely underlying mechanisms. In addition, the pre‐existing chronic liver disease …