Hepatitis C virus core protein activates nuclear factor κB-dependent signaling through tumor necrosis factor receptor-associated factor
H Yoshida, N Kato, Y Shiratori, M Otsuka… - Journal of Biological …, 2001 - ASBMB
Hepatitis C virus (HCV) core protein, a viral nucleocapsid, has been shown to affect various
intracellular events including the nuclear factor κB (NF-κB) signaling supposedly associated
with inflammatory response, cell proliferation, and apoptosis. In order to elucidate the effect
of HCV core protein on the NF-κB signaling in HeLa and HepG2 cells, a reporter assay was
utilized. HCV core protein significantly activated NF-κB signaling in a dose-dependent
manner not only in HeLa and HepG2 cells transiently transfected with core protein …
intracellular events including the nuclear factor κB (NF-κB) signaling supposedly associated
with inflammatory response, cell proliferation, and apoptosis. In order to elucidate the effect
of HCV core protein on the NF-κB signaling in HeLa and HepG2 cells, a reporter assay was
utilized. HCV core protein significantly activated NF-κB signaling in a dose-dependent
manner not only in HeLa and HepG2 cells transiently transfected with core protein …
以上显示的是最相近的搜索结果。 查看全部搜索结果