LE Wagenknecht, AL Scherzinger, ER Stamm… - …, 2009 - Wiley Online Library
… liver density is more strongly genetic. The only other reports of heritability come from studies in which biochemical liver … Our findings of modest heritability support future efforts to map …
NMW de Alwis, CP Day - Seminars in liver disease, 2007 - thieme-connect.com
… steatohepatitis, fibrosis, and cirrhosis. Genetic and environmental risk factors for advanced alcoholicliverdisease (ALD) and nonalcoholicfattyliverdisease (NAFLD) seem likely to …
P Dongiovanni, L Valenti - Metabolism, 2016 - Elsevier
… non-alcoholicfattyliverdisease, now the leading cause of liver damage in developed countries, has a strong heritability. … the major genetic determinant of hepatic fat content. The I148M …
S Sookoian, CJ Pirola - Clinical and molecular hepatology, 2017 - ncbi.nlm.nih.gov
… In this review, we focused on the genetic component of NAFLD, with special emphasis on the role of genetics in the disease pathogenesis and natural history. Insights into the topic of …
V Ajmera, R Loomba - Current opinion in gastroenterology, 2023 - journals.lww.com
… Nonalcoholicfattyliverdisease (NAFLD) is the most common cause of liverdisease in the United States and has a strong heritable component. Advances in understanding the genetic …
QM Anstee, CP Day - Seminars in liver disease, 2015 - thieme-connect.com
… steatohepatitis (NASH) to fibrosis and ultimately cirrhosis. Nonalcoholicfattyliverdisease is characterized by substantial interpatient variation in rate of progression and disease …
…, D Brenner, Genetics of NAFLD in Twins Consortium - Gastroenterology, 2015 - Elsevier
… Little is known about the heritability of hepatic fibrosis, and the heritability of hepaticsteatosis … Twenty-six of the 120 subjects (21.7%) had nonalcoholicfattyliverdisease (defined as MRI-…
… alcoholicliverdisease (ALD) and metabolic syndrome-related nonalcoholicfattyliver disease (NAFLD) are recognized as the most common causes of liver dysfunction worldwide. …
S Sookoian, CJ Pirola - Seminars in liver disease, 2019 - thieme-connect.com
… the biology of nonalcoholicfattyliverdisease (NAFLD) and nonalcoholic steatohepatitis (NASH). The … 1 Missing heritability of nonalcoholicfattyliverdisease (NAFLD) and nonalcoholic …