Heritability of nonalcoholic fatty liver disease

JB Schwimmer, MA Celedon, JE Lavine, R Salem… - Gastroenterology, 2009 - Elsevier
liver fat fraction and the condition of fatty liver are heritable traits. The estimate for the heritability
of the fatty liver … value for the heritability of fatty liver, but confidently can conclude that the …

Correlates and heritability of nonalcoholic fatty liver disease in a minority cohort

LE Wagenknecht, AL Scherzinger, ER Stamm… - …, 2009 - Wiley Online Library
liver density is more strongly genetic. The only other reports of heritability come from studies
in which biochemical liver … Our findings of modest heritability support future efforts to map …

Genetics of alcoholic liver disease and nonalcoholic fatty liver disease

NMW de Alwis, CP Day - Seminars in liver disease, 2007 - thieme-connect.com
… steatohepatitis, fibrosis, and cirrhosis. Genetic and environmental risk factors for advanced
alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) seem likely to …

Genetics of nonalcoholic fatty liver disease

P Dongiovanni, L Valenti - Metabolism, 2016 - Elsevier
non-alcoholic fatty liver disease, now the leading cause of liver damage in developed countries,
has a strong heritability. … the major genetic determinant of hepatic fat content. The I148M …

[HTML][HTML] Genetic predisposition in nonalcoholic fatty liver disease

S Sookoian, CJ Pirola - Clinical and molecular hepatology, 2017 - ncbi.nlm.nih.gov
… In this review, we focused on the genetic component of NAFLD, with special emphasis on
the role of genetics in the disease pathogenesis and natural history. Insights into the topic of …

Advances in the genetics of nonalcoholic fatty liver disease

V Ajmera, R Loomba - Current opinion in gastroenterology, 2023 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in the
United States and has a strong heritable component. Advances in understanding the genetic …

The genetics of nonalcoholic fatty liver disease: spotlight on PNPLA3 and TM6SF2

QM Anstee, CP Day - Seminars in liver disease, 2015 - thieme-connect.com
… steatohepatitis (NASH) to fibrosis and ultimately cirrhosis. Nonalcoholic fatty liver disease
is characterized by substantial interpatient variation in rate of progression and disease

Heritability of hepatic fibrosis and steatosis based on a prospective twin study

…, D Brenner, Genetics of NAFLD in Twins Consortium - Gastroenterology, 2015 - Elsevier
… Little is known about the heritability of hepatic fibrosis, and the heritability of hepatic steatosis
… Twenty-six of the 120 subjects (21.7%) had nonalcoholic fatty liver disease (defined as MRI-…

Genetics of alcoholic and nonalcoholic fatty liver disease

QM Anstee, AK Daly, CP Day - Seminars in liver disease, 2011 - thieme-connect.com
alcoholic liver disease (ALD) and metabolic syndrome-related nonalcoholic fatty liver
disease (NAFLD) are recognized as the most common causes of liver dysfunction worldwide. …

Genetics of nonalcoholic fatty liver disease: from pathogenesis to therapeutics

S Sookoian, CJ Pirola - Seminars in liver disease, 2019 - thieme-connect.com
… the biology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).
The … 1 Missing heritability of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic