Post-sequencing genomic data analysis becomes a major challenge while next-generation
sequencing technologies evolve by leaps and bounds. The data-intensive and compute-
intensive nature of genome analysis makes cluster computing an attractive choice for
building efficient solutions. This paper presents HiGene, a high-performance genome
analysis platform that exploits big data technology to revolutionize genomics data crunching
power. HiGene reconstructs the genome analysis pipeline by exploiting both multi-core and …