[HTML][HTML] High throughput phenotyping for dimensional psychopathology in electronic health records

TH McCoy Jr, S Yu, KL Hart, VM Castro, HE Brown… - Biological …, 2018 - Elsevier
Background Relying on diagnostic categories of neuropsychiatric illness obscures the
complexity of these disorders. Capturing multiple dimensional measures of neuropathology
could facilitate the clinical and neurobiological investigation of cognitive and behavioral
phenotypes. Methods We developed a natural language processing–based approach to
extract five symptom dimensions, based on the National Institute of Mental Health Research
Domain Criteria definitions, from narrative clinical notes. Estimates of Research Domain …
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