Histone H3K56 acetylation is required for quelling-induced small RNA production through its role in homologous recombination
Z Zhang, Q Yang, G Sun, S Chen, Q He, S Li… - Journal of Biological …, 2014 - ASBMB
Quelling and DNA damage-induced small RNA (qiRNA) production are RNA interference
(RNAi)-related phenomenon from repetitive genomic loci in Neurospora. We have recently
proposed that homologous recombination from repetitive DNA loci allows the RNAi pathway
to recognize repetitive DNA to produce small RNA. However, the mechanistic detail of this
pathway remains largely unclear. By systematically screening the Neurospora knock-out
library, we identified RTT109 as a novel component required for small RNA production …
(RNAi)-related phenomenon from repetitive genomic loci in Neurospora. We have recently
proposed that homologous recombination from repetitive DNA loci allows the RNAi pathway
to recognize repetitive DNA to produce small RNA. However, the mechanistic detail of this
pathway remains largely unclear. By systematically screening the Neurospora knock-out
library, we identified RTT109 as a novel component required for small RNA production …
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