Honey mitigates radiation-induced oral mucositis in head and neck cancer patients without affecting the tumor response

S Rao, SK Hegde, P Rao, C Dinkar, KR Thilakchand… - Foods, 2017 - mdpi.com
Radiation-induced mucositis is a dose-limiting factor in the effective treatment of head and
neck (H & N) cancers. The objective of this study was to understand the efficacy of honey in
mitigating radiation-induced mucositis and whether it would interfere with tumor control. This
was a single-blinded, randomized, controlled study and was carried out in patients with H &
N cancer requiring curative radiotherapy (> 62 Gy (Gray)). The patients meeting the
inclusion criteria were randomly assigned to receive either honey (n= 25) or povidone …

Honey Against Radiation-induced Oral Mucositis in Head and Neck Cancer Patients. An Umbrella Review of Systematic Reviews and Meta-Analyses of the Literature

A Gkantaifi, F Alongi, E Vardas, F Cuccia… - Reviews on Recent …, 2020 - ingentaconnect.com
Backround: Oral mucositis (OM) consists of a major side effect of radiotherapy (RT) in head
and neck (HN) cancer patients and natural honey is gaining more and more scientific
interest due to its beneficial effects in tissue repair. Objective: The aim of this review is to
better clarify the preventive/therapeutic role of honey in the management of OM in patients
with HN cancer undergoing RT with or without chemotherapy (CT). Methods: We used the
PubMed database to retrieve journal articles and the inclusion criteria were only reviews …
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