Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity
AT Tromp, M Van Gent, JP Jansen, LM Scheepmaker… - Toxins, 2020 - mdpi.com
Staphylococcal bi-component pore-forming toxins, also known as leukocidins, target and
lyse human phagocytes in a receptor-dependent manner. S-components of the leukocidins
Panton-Valentine leukocidin (PVL), γ-haemolysin AB (HlgAB) and CB (HlgCB), and
leukocidin ED (LukED) specifically employ receptors that belong to the class of G-protein
coupled receptors (GPCRs). Although these receptors share a common structural
architecture, little is known about the conserved characteristics of the interaction between …
lyse human phagocytes in a receptor-dependent manner. S-components of the leukocidins
Panton-Valentine leukocidin (PVL), γ-haemolysin AB (HlgAB) and CB (HlgCB), and
leukocidin ED (LukED) specifically employ receptors that belong to the class of G-protein
coupled receptors (GPCRs). Although these receptors share a common structural
architecture, little is known about the conserved characteristics of the interaction between …
Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity
V Gent, D Haas, V Kessel, V Strijp - agris.fao.org
Staphylococcal bi-component pore-forming toxins, also known as leukocidins, target and
lyse human phagocytes in a receptor-dependent manner. S-components of the leukocidins
Panton-Valentine leukocidin (PVL), &gamma:-haemolysin AB (HlgAB) and CB (HlgCB), and
leukocidin ED (LukED) specifically employ receptors that belong to the class of G-protein
coupled receptors (GPCRs). Although these receptors share a common structural
architecture, little is known about the conserved characteristics of the interaction between …
lyse human phagocytes in a receptor-dependent manner. S-components of the leukocidins
Panton-Valentine leukocidin (PVL), &gamma:-haemolysin AB (HlgAB) and CB (HlgCB), and
leukocidin ED (LukED) specifically employ receptors that belong to the class of G-protein
coupled receptors (GPCRs). Although these receptors share a common structural
architecture, little is known about the conserved characteristics of the interaction between …
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