Host–pathogen interactome analysis of Chikungunya virus envelope proteins E1 and E2
The envelope proteins of Chikungunya virus (CHIKV) are known to play crucial roles in viral
infection and spread. Although the role of envelope proteins in viral infection has been
studied, the cellular interactors of these proteins are still elusive. In the present study, the
ectodomains of CHIKV envelope proteins (E1 and E2) have been used for a high throughput
yeast two-hybrid (Y2H) screening to identify the interacting host protein partners. Following a
comparative analysis between the viral–host protein interaction data generated from Y2H …
infection and spread. Although the role of envelope proteins in viral infection has been
studied, the cellular interactors of these proteins are still elusive. In the present study, the
ectodomains of CHIKV envelope proteins (E1 and E2) have been used for a high throughput
yeast two-hybrid (Y2H) screening to identify the interacting host protein partners. Following a
comparative analysis between the viral–host protein interaction data generated from Y2H …
Host-pathogen interactome analysis of Chikungunya virus envelope proteins E1 and E2.
ND Namrata Dudha, JR Jyoti Rana… - 2015 - cabidigitallibrary.org
The envelope proteins of Chikungunya virus (CHIKV) are known to play crucial roles in viral
infection and spread. Although the role of envelope proteins in viral infection has been
studied, the cellular interactors of these proteins are still elusive. In the present study, the
ectodomains of CHIKV envelope proteins (E1 and E2) have been used for a high throughput
yeast two-hybrid (Y2H) screening to identify the interacting host protein partners. Following a
comparative analysis between the viral-host protein interaction data generated from Y2H …
infection and spread. Although the role of envelope proteins in viral infection has been
studied, the cellular interactors of these proteins are still elusive. In the present study, the
ectodomains of CHIKV envelope proteins (E1 and E2) have been used for a high throughput
yeast two-hybrid (Y2H) screening to identify the interacting host protein partners. Following a
comparative analysis between the viral-host protein interaction data generated from Y2H …
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