Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs
Angiogenesis is a complex process that is required for development and tissue regeneration
and it may be affected by many pathological conditions. Chemicals and drugs can impact
formation and maintenance of the vascular networks; these effects may be both desirable
(eg, anti-cancer drugs) or unwanted (eg, side effects of drugs). A number of in vivo and in
vitro models exist for studies of angiogenesis and endothelial cell function, including organ-
on-a-chip microphysiological systems. An arrayed organ-on-a-chip platform on a 96-well …
and it may be affected by many pathological conditions. Chemicals and drugs can impact
formation and maintenance of the vascular networks; these effects may be both desirable
(eg, anti-cancer drugs) or unwanted (eg, side effects of drugs). A number of in vivo and in
vitro models exist for studies of angiogenesis and endothelial cell function, including organ-
on-a-chip microphysiological systems. An arrayed organ-on-a-chip platform on a 96-well …
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