Human stroma and epithelium co-culture in a microfluidic model of a human prostate gland

L Jiang, F Ivich, S Tahsin, M Tran, SB Frank… - …, 2019 - pubs.aip.org
The prostate is a walnut-sized gland that surrounds the urethra of males at the base of the
bladder comprising a muscular portion, which controls the release of urine, and a glandular
portion, which secretes fluids that nourish and protect sperms. Here, we report the
development of a microfluidic-based model of a human prostate gland. The
polydimethylsiloxane (PDMS) microfluidic device, consisting of two stacked microchannels
separated by a polyester porous membrane, enables long-term in vitro cocultivation of …
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