Hydrodynamics and heat transfer from single circular cylinder with yaw angle were examined in the current study. During the experiment the distribution of the Nusselt number on the surface and the 3D velocity field (using stereo-PIV) in the cylinder wake were acquired simultaneously. Experiments were conducted with constant wall temperature conditions, for yaw angles β/°: 90 (cross-flow), 85, 75, 70, 65, 50 and 45; and Reynolds numbers Re: 10 4, 1.3× 10 4, 2.6× 10 4, 4.7× 10 4 and 7.9× 10 4. The results showed the minimum in surface-averaged Nusselt number Nu‾ for yaw angles β/° between 70 and 65. For β/°⩽ 65 surface-averaged Nusselt number Nu‾ increases up to 32%(at β/°= 45, Re= 7.9× 10 4) compared with the cross-flow case. Both decrease and increase of Nu‾ is induced by changes of a flow pattern in the wake of the cylinder and, as a result, changes in a velocity field in the vicinity of a rear cylinder surface.