Hydroxyapatite-supported Cu (i)-catalysed cyanation of styrenyl bromides with K 4 [Fe (CN) 6]: an easy access to cinnamonitriles
Organic & Biomolecular Chemistry, 2012•pubs.rsc.org
An efficient cyanation of styrenyl bromides by K4 [Fe (CN) 6] has been achieved under the
catalysis of hydroxyapatite-supported copper (I) producing a variety of functionalized
cinnamonitriles in high yields. The stereochemistry of the styrenyl double bond is preserved
during the process providing the same stereoisomer of product.
catalysis of hydroxyapatite-supported copper (I) producing a variety of functionalized
cinnamonitriles in high yields. The stereochemistry of the styrenyl double bond is preserved
during the process providing the same stereoisomer of product.
An efficient cyanation of styrenyl bromides by K4[Fe(CN)6] has been achieved under the catalysis of hydroxyapatite-supported copper(I) producing a variety of functionalized cinnamonitriles in high yields. The stereochemistry of the styrenyl double bond is preserved during the process providing the same stereoisomer of product.
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