Hyperhomocysteinaemia and factor V Leiden mutation are associated with Budd–Chiari syndrome
Y Colak, Z Karasu, N Oruc, C Can… - European journal of …, 2006 - journals.lww.com
Objectives Budd–Chiari syndrome (BCS) is characterized by hepatic venous outflow
obstruction and may be caused by various prothrombotic disorders. We aimed to study the
role of hyperhomocysteinaemia, factor V Leiden mutation and G20210A prothrombin gene
mutation in the pathogenesis of the syndrome. Methods Thirty-two patients (16 male, 16
female, aged 19–45 years) with angiographically verified BCS and 33 age-matched and sex-
matched voluntary healthy controls (15 male, 18 female, aged 19–45 years) were included …
obstruction and may be caused by various prothrombotic disorders. We aimed to study the
role of hyperhomocysteinaemia, factor V Leiden mutation and G20210A prothrombin gene
mutation in the pathogenesis of the syndrome. Methods Thirty-two patients (16 male, 16
female, aged 19–45 years) with angiographically verified BCS and 33 age-matched and sex-
matched voluntary healthy controls (15 male, 18 female, aged 19–45 years) were included …
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