Hypersexuality and paraphilia induced by selegiline in Parkinson's disease: report of 2 cases

MA Shapiro, YL Chang, SK Munson, MS Okun… - Parkinsonism & related …, 2006 - Elsevier
MA Shapiro, YL Chang, SK Munson, MS Okun, HH Fernandez
Parkinsonism & related disorders, 2006Elsevier
While hypersexuality and paraphilia are known side effects of anti-Parkinson medications, it
is seldom reported. Furthermore, selegiline is rarely implicated in such behaviors. We report
two cases of early onset PD who experienced paraphilia and hypersexuality when selegiline
was initiated, and later developing obsessive–compulsive and punding behavior with the
addition of dopamine agonists. Social repercussions may prohibit patients and/or their
families from volunteering such information.
While hypersexuality and paraphilia are known side effects of anti-Parkinson medications, it is seldom reported. Furthermore, selegiline is rarely implicated in such behaviors. We report two cases of early onset PD who experienced paraphilia and hypersexuality when selegiline was initiated, and later developing obsessive–compulsive and punding behavior with the addition of dopamine agonists. Social repercussions may prohibit patients and/or their families from volunteering such information.
Elsevier
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