IL-15 and GM-CSF stimulated macrophages enhances phagocytic activity in ENU induced leukemic mice
AK Singha, C Sarkar, D Majumder, R Debnath, M Saha… - Immunobiology, 2020 - Elsevier
Murine splenic macrophage plays a decisive role in host immunity through phagocytosis
against pathogens. It was reported that, macrophages also involves in phagocytosis of some
tumour cells upon its activation initiated by certain cytokines produced by other immune cell
or by indigenously treated. In this study, we have investigated the killing of leukemic blast
cells by macrophages upon stimulated with IL-15 and GM-CSF alone or in combination in
ENU challenged leukemic murine model. Along with, the release of TNF-α, IL-12 and IFN-γ …
against pathogens. It was reported that, macrophages also involves in phagocytosis of some
tumour cells upon its activation initiated by certain cytokines produced by other immune cell
or by indigenously treated. In this study, we have investigated the killing of leukemic blast
cells by macrophages upon stimulated with IL-15 and GM-CSF alone or in combination in
ENU challenged leukemic murine model. Along with, the release of TNF-α, IL-12 and IFN-γ …
以上显示的是最相近的搜索结果。 查看全部搜索结果