Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression
TP Hsieh, SY Sheu, JS Sun, MH Chen, MH Liu - Phytomedicine, 2010 - Elsevier
Epimedii herba is one of the most frequently used herbs in formulas prescribed for the
treatment of osteoporosis in China. The main active flavonoid glucoside extracted from
Epimedium pubescens is Icariin, which has been reported to enhance bone healing and
reduce osteoporosis occurrence. However, the detailed molecular mechanisms remain
unclear. In this present study, we examine the molecular mechanisms of icariin by using
primary osteoblast cell cultures obtained from adult mice. The osteoblast cells were …
treatment of osteoporosis in China. The main active flavonoid glucoside extracted from
Epimedium pubescens is Icariin, which has been reported to enhance bone healing and
reduce osteoporosis occurrence. However, the detailed molecular mechanisms remain
unclear. In this present study, we examine the molecular mechanisms of icariin by using
primary osteoblast cell cultures obtained from adult mice. The osteoblast cells were …
Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression.
HTP Hsieh TsaiPei, SSY Sheu ShiowYunn… - 2010 - cabidigitallibrary.org
Epimedii herba is one of the most frequently used herbs in formulas prescribed for the
treatment of osteoporosis in China. The main active flavonoid glucoside extracted from
Epimedium pubescens is Icariin, which has been reported to enhance bone healing and
reduce osteoporosis occurrence. However, the detailed molecular mechanisms remain
unclear. In this present study, we examine the molecular mechanisms of icariin by using
primary osteoblast cell cultures obtained from adult mice. The osteoblast cells were …
treatment of osteoporosis in China. The main active flavonoid glucoside extracted from
Epimedium pubescens is Icariin, which has been reported to enhance bone healing and
reduce osteoporosis occurrence. However, the detailed molecular mechanisms remain
unclear. In this present study, we examine the molecular mechanisms of icariin by using
primary osteoblast cell cultures obtained from adult mice. The osteoblast cells were …
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