Particle tracking is a widely used and promising technique for elucidating complex dynamics
of the living cell. The cytoplasm is an active material, in which the kinetics of intracellular
structures are highly heterogeneous. Tracer particles typically undergo a combination of
random motion and various types of directed motion caused by the activity of molecular
motors and other non-equilibrium processes. Random switching between more and less
directional persistence of motion generally occurs. We present a method for identifying …