IgG-antibodies are potent and versatile mediators of host protection. They elicit their
biological effects through specific interaction of the Fc-part with complement, specific cellular
receptors, or both. Several factors should be taken into consideration when analyzing the
nature and intensity of the immunological response elicited via IgG-effector functions,
especially for the family of IgG-Fc receptors (FcγRs) exclusively expressed on immune cells.
These include the various classes of leukocyte FcγR, expressed variably on different …