Advances in the quality of whole-slide images have set the stage for the clinical use of digital
images in anatomic pathology. Along with advances in computer image analysis, this raises
the possibility for computer-assisted diagnostics in pathology to improve histopathologic
interpretation and clinical care. To evaluate the potential impact of digital assistance on
interpretation of digitized slides, we conducted a multireader multicase study utilizing our
deep learning algorithm for the detection of breast cancer metastasis in lymph nodes. Six …