offspring with MNU-induced microcephaly were examined on the Biel water maze and its
mirror-image maze at 6 weeks of age and on a radial eight-arm maze at 14 weeks of age.
The MNU rats showed postnatal depression in body weight. Their brain weight was about
60% of the control value, and they were thus microcephalic. The MNU animals made
significantly more errors on the Biel maze and its mirror-image maze than the controls. In the …