Impaired toll like receptor 9 response in pulmonary tuberculosis
K Ramakrishna, K Premkumar, J Kabeerdoss, KR John - Cytokine, 2017 - Elsevier
Background & aim Innate immune responses are important in susceptibility to pulmonary
tuberculosis (TB). In order to test the hypothesis that Toll-like receptor (TLR) 2 function would
be abnormal in patients with active pulmonary TB we compared the cytokine responses of
peripheral blood mononuclear cells (PBMC) to innate immune ligands in a case-control
study. Methods PBMC from 19 untreated pulmonary TB patients, 17 healthy controls, and 11
treated pulmonary TB patients, were cultured for 24 h with TLR 2 ligand (PAM-CSK) and …
tuberculosis (TB). In order to test the hypothesis that Toll-like receptor (TLR) 2 function would
be abnormal in patients with active pulmonary TB we compared the cytokine responses of
peripheral blood mononuclear cells (PBMC) to innate immune ligands in a case-control
study. Methods PBMC from 19 untreated pulmonary TB patients, 17 healthy controls, and 11
treated pulmonary TB patients, were cultured for 24 h with TLR 2 ligand (PAM-CSK) and …
Impaired toll like receptor 9 response in pulmonary tuberculosis.
KR Kartik Ramakrishna, KP Kalpana Premkumar… - 2017 - cabidigitallibrary.org
Background & aim: Innate immune responses are important in susceptibility to pulmonary
tuberculosis (TB). In order to test the hypothesis that Toll-like receptor (TLR) 2 function would
be abnormal in patients with active pulmonary TB we compared the cytokine responses of
peripheral blood mononuclear cells (PBMC) to innate immune ligands in a case-control
study. Methods: PBMC from 19 untreated pulmonary TB patients, 17 healthy controls, and 11
treated pulmonary TB patients, were cultured for 24 h with TLR 2 ligand (PAM-CSK) and …
tuberculosis (TB). In order to test the hypothesis that Toll-like receptor (TLR) 2 function would
be abnormal in patients with active pulmonary TB we compared the cytokine responses of
peripheral blood mononuclear cells (PBMC) to innate immune ligands in a case-control
study. Methods: PBMC from 19 untreated pulmonary TB patients, 17 healthy controls, and 11
treated pulmonary TB patients, were cultured for 24 h with TLR 2 ligand (PAM-CSK) and …
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