Impaired vitamin D signaling in endothelial cell leads to an enhanced leukocyte-endothelium interplay: implications for atherosclerosis development
M Bozic, Á Álvarez, C de Pablo, MD Sanchez-Niño… - PLoS …, 2015 - journals.plos.org
Endothelial cell activation leading to leukocyte recruitment and adhesion plays an essential
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective
actions, while its deficiency is a risk factor for the progression of cardiovascular damage. Our
aim was to assess the role of basal levels of vitamin D receptor (VDR) on the early leukocyte
recruitment and related endothelial cell-adhesion-molecule expression, as essential
prerequisites for the onset of atherosclerosis. Knockdown of VDR in endothelial cells …
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective
actions, while its deficiency is a risk factor for the progression of cardiovascular damage. Our
aim was to assess the role of basal levels of vitamin D receptor (VDR) on the early leukocyte
recruitment and related endothelial cell-adhesion-molecule expression, as essential
prerequisites for the onset of atherosclerosis. Knockdown of VDR in endothelial cells …
[PDF][PDF] Impaired Vitamin D Signaling in Endothelial Cell Leads to an Enhanced Leukocyte-Endothelium Interplay: Implications for Atherosclerosis Development
X Dolcet Roca, M Encinas Martín, M Bozic, Á Álvarez… - 2015 - repositori.udl.cat
Endothelial cell activation leading to leukocyte recruitment and adhesion plays an essential
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective
actions, while its deficiency is a risk factor for the progression of cardiovascular damage. Our
aim was to assess the role of basal levels of vitamin D receptor (VDR) on the early leukocyte
recruitment and related endothelial cell-adhesion-molecule expression, as essential
prerequisites for the onset of atherosclerosis. Knockdown of VDR in endothelial cells …
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective
actions, while its deficiency is a risk factor for the progression of cardiovascular damage. Our
aim was to assess the role of basal levels of vitamin D receptor (VDR) on the early leukocyte
recruitment and related endothelial cell-adhesion-molecule expression, as essential
prerequisites for the onset of atherosclerosis. Knockdown of VDR in endothelial cells …
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