Improved axial position detection in optical tweezers measurements

JK Dreyer, K Berg-Sørensen, L Oddershede - Applied Optics, 2004 - opg.optica.org
Applied Optics, 2004opg.optica.org
We investigate the axial position detection of a trapped microsphere in an optical trap by
using a quadrant photodiode. By replacing the photodiode with a CCD camera, we obtain
detailed information on the light scattered by the microsphere. The correlation of the
interference pattern with the axial position displays complex behavior with regions of
positive and negative interference. By analyzing the scattered light intensity as a function of
the axial position of the trapped sphere, we propose a simple method to increase the …
We investigate the axial position detection of a trapped microsphere in an optical trap by using a quadrant photodiode. By replacing the photodiode with a CCD camera, we obtain detailed information on the light scattered by the microsphere. The correlation of the interference pattern with the axial position displays complex behavior with regions of positive and negative interference. By analyzing the scattered light intensity as a function of the axial position of the trapped sphere, we propose a simple method to increase the sensitivity and control the linear range of axial position detection.
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