In depth investigation of the retention behavior of structurally related β-blockers on RP-HPLC column: Quality by design and quantitative structure-property relationship …
The persistent introduction of new β-blockers motivates the demand for optimizing RP-HPLC
well-designed analytical procedures that could be applied to this structurally related and
commonly prescribed pharmacological group in order to reduce time and chemicals
consumption in quality control units. Betoxolol HCl (BEX) and Carvidolol (CAR) were
selected as representative examples to conduct predictive studies based on two
complementary approaches, Quality by design (QBD) and Quantitative structure property …
well-designed analytical procedures that could be applied to this structurally related and
commonly prescribed pharmacological group in order to reduce time and chemicals
consumption in quality control units. Betoxolol HCl (BEX) and Carvidolol (CAR) were
selected as representative examples to conduct predictive studies based on two
complementary approaches, Quality by design (QBD) and Quantitative structure property …
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