In human genome, generation of a nuclear export signal through duplication appears unique to nucleophosmin (NPM1) mutations and is restricted to AML

A Liso, A Bogliolo, V Freschi, MP Martelli, SA Pileri… - Leukemia, 2008 - nature.com
A Liso, A Bogliolo, V Freschi, MP Martelli, SA Pileri, M Santodirocco, N Bolli, MF Martelli…
Leukemia, 2008nature.com
2 Heil G, Hoelzer D, Sanz MA, Lechner K, Noens L, Szer J et al. Long-term survival data
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2 Heil G, Hoelzer D, Sanz MA, Lechner K, Noens L, Szer J et al. Long-term survival data from a phase 3 study of Filgrastim as an adjunct to chemotherapy in adults with de novo acute myeloid leukemia. Leukemia 2006; 20: 404–409. 3 Ohno R, Tomonaga M, Kobayashi T, Kanamaru A, Shirakawa S, Masaoka T et al. Effect of granulocyte colony-stimulating factor after intensive induction therapy in relapsed or refractory acute leukemia.
nature.com
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