In vivo X-ray imaging of phosphor-doped PDMS and phosphor-doped aerogel biomaterials

SW Allison, ES Baker, KJ Lynch… - International Journal of …, 2015 - Taylor & Francis
International Journal of Polymeric Materials and Polymeric Biomaterials, 2015Taylor & Francis
Noninvasive rapid in vivo imaging and detection of biomedical implants is a critical part of
the design and implementation of smart implants. Thermographic phosphors offer a precise
and remotely accessible sensing method that has been utilized here. We present the first in
vivo X-ray images of La2O2S: Eu-doped crosslinked silica aerogels and
polydimethylsiloxane (PDMS) with increasing dopant concentrations. Results show that
native PDMS and crosslinked silica aerogel do not show noticeable attenuation of X-rays …
Noninvasive rapid in vivo imaging and detection of biomedical implants is a critical part of the design and implementation of smart implants. Thermographic phosphors offer a precise and remotely accessible sensing method that has been utilized here. We present the first in vivo X-ray images of La2O2S:Eu-doped crosslinked silica aerogels and polydimethylsiloxane (PDMS) with increasing dopant concentrations. Results show that native PDMS and crosslinked silica aerogel do not show noticeable attenuation of X-rays while image analysis yields values of the absorption coefficient of 0.014 for the doped aerogel and a range of 0.015–0.017 for the doped PDMS.
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