[HTML][HTML] In vivo anti-typhoid and safety evaluation of extracts of Ximenia americana on experimental rats
HL Muhammad, R Garba, AS Abdullah… - Pharmacological …, 2021 - Elsevier
Background Typhoid fever is an infectious disease of serious public health concern. The anti-
typhoid efficacy and safety of Ximenia americana stem bark extracts on the nephrocytes,
hepatocytes, and haematological parameters of Salmonella typhi infected Wistar albino rats
was evaluated. Methodology Experimental rats in their respective groups were infected with
S. typhi via oral administration of infective dose (0.5 ml of 1.5× 10 4 cfu/ml) of cultured S.
typhi, while group 1 were uninfected. Group 2 were untreated, group 3 were treated with the …
typhoid efficacy and safety of Ximenia americana stem bark extracts on the nephrocytes,
hepatocytes, and haematological parameters of Salmonella typhi infected Wistar albino rats
was evaluated. Methodology Experimental rats in their respective groups were infected with
S. typhi via oral administration of infective dose (0.5 ml of 1.5× 10 4 cfu/ml) of cultured S.
typhi, while group 1 were uninfected. Group 2 were untreated, group 3 were treated with the …
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