Increased levels of adipose tissue-resident Th17 cells in obesity associated with miR-326
M Vega-Cárdenas, EE Uresti-Rivera… - Immunology letters, 2019 - Elsevier
Abstract miRNAs are important immune regulators in the control of the CD4+ T cells
phenotype. miR-326 regulates the differentiation towards Th17 cells and the inhibition of
miR-155 is associated with low levels of Treg cells. However, miRNAs expression and
transcription factors associated with these lymphocyte subsets in obesity-induced adipose
tissue inflammation is still unknown. The aim of this work was to identify Th17 cells in
subcutaneous adipose tissue (SAT), proinflammatory cytokine production and their …
phenotype. miR-326 regulates the differentiation towards Th17 cells and the inhibition of
miR-155 is associated with low levels of Treg cells. However, miRNAs expression and
transcription factors associated with these lymphocyte subsets in obesity-induced adipose
tissue inflammation is still unknown. The aim of this work was to identify Th17 cells in
subcutaneous adipose tissue (SAT), proinflammatory cytokine production and their …
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