In this paper, we propose the conjunction of the Smart City Initiative and the concept of Industry 4.0. The term smart city has been a phenomenon of the last years, which is very inflected especially since 2008 when the world was hit by the financial crisis. The main reasons for the emergence of the Smart City Initiative are to create a sustainable model for cities and preserve quality of life of their citizens. The topic of the smart city cannot be seen only as a technical discipline, but different economic, humanitarian or legal aspects must be involved as well. In the concept of Industry 4.0, the Internet of Things (IoT) shall be used for the development of so-called smart products. Sub-components of the product are equipped with their own intelligence. Added intelligence is used both during the manufacturing of a product as well as during subsequent handling, up to continuous monitoring of the product lifecycle (smart processes). Other important aspects of the Industry 4.0 are Internet of Services (IoS), which includes especially intelligent transport and logistics (smart mobility, smart logistics), as well as Internet of Energy (IoE), which determines how the natural resources are used in proper way (electricity, water, oil, etc.). IoT, IoS, IoP and IoE can be considered as an element that can create a connection of the Smart City Initiative and Industry 4.0 - Industry 4.0 can be seen as a part of smart cities. Interconnection of these systems can be expected to change - transport processes from design logistic processes through to their online optimization with respect to the chosen objective function and the latest information from the transport infrastructure. Linking information from process-based Industry 4.0 with intelligent transport systems of the smart city could create very effective, demand-oriented and higher productivity of manufacturing enterprises as well as sustainable development of society.