… t,o infer tlomairl-dorrlairl int,cxractions from the, 5719 yeast protein-protein interactions ol)t,…
,ivit,y; (2) our predicted protein-protein interactions havta a significant overlap with the MIPS(…

… likely rely on domain-domain interactions (DDIs). Several attempts exist to infer DDIs from
… called “PPIDM” (Protein-Protein Interactions Domain Miner) for inferring DDIs using multiple …

… principle, namely, domain–domain interactions. The protein … unit for protein–protein
interactions. Therefore, it is important to take into account domain–domain interactions when we infer …

… used a conserved binding mode analysis on domain–domain interactions inferred from
PDB crystal structures to detect binding surfaces of biological relevance. Neduva et al. studied …

… the set of inferred DDIs and the set of DDIs confirmed to interact by 3D crystal … domain-domain
interactions (GDDIs). This ideal is desirable not only to tease out specific interactions …

… is used to infer domain-domain interactions from given protein interaction data. Guimarães
… (PE) approach to predict domain-domain interactions from protein interactions [10], in which …

… interactions among proteins where only domain composition is known. Based on the currently
available protein–protein interaction … predict potential protein–protein interactions. Utilizing …

… based methods to infer domain interactions have been … For this, we first form a list of all
possible domain-domain interactions … total of the domain-domain interaction scores to represent …

… We augment our observed data (protein-protein interactions and the domains on the proteins)
with missing data (the unobserved domain-domain interactions) to obtain what is known in …

… Intuitively, a IDPP is meant to gather all the evidences from MS about a given domain-domain
interaction. IDPPs for which the two SIC are not degenerated (1:n and n:n) can be …