The relationship between bisphosphonates (BP) and dental implant failure has not been
fully elucidated. The purpose of this retrospective radiographic study was to examine
whether patients who take BP are at greater risk of implant failure than patients not using
those agents. Treatment records of 362 consecutively treated patients receiving endosseous
dental implants were reviewed. The patient population consisted of 227 women and 135
men with a mean age of 56 years (range: 17–87 years), treated in the University at Buffalo …

Materials and Methods: A randomized controlled trial was undertaken with a sample size of
60 individuals who were implanted with orally integrated dental implants. Study participants
were split into two groups: Group A (n= 30) had bisphosphonate therapy for a minimum of 1
year before implant placement, while Group B (n= 30) did not have any bisphosphonate
treatment. Cone beam computed tomography images were performed to quantify the
alveolar bone levels surrounding the implants at three time points: baseline, 6 months, and …