A modern-day society demands resilient, reliable, and smart urban infrastructure for effective and in telligent operations and deployment. However, unexpected, high-impact, and low-probability events such as earthquakes, tsunamis, tornadoes, and hurricanes make the design of such robust infrastructure more complex. As a result of such events, a power system infrastructure can be severely affected, leading to unprecedented events, such as blackouts. Nevertheless, the integration of smart grids into the existing framework of smart cities adds to their resilience. Therefore, designing a resilient and reliable power system network is an inevitable requirement of modern smart city infras tructure. With the deployment of the Internet of Things (IoT), smart cities infrastructures have taken a transformational turn towards introducing technologies that do not only provide ease and comfort to the citizens but are also feasible in terms of sustainability and dependability. This paper presents a holistic view of a resilient and sustainable smart city architecture that utilizes IoT, big data analytics, unmanned aerial vehicles, and smart grids through intelligent integration of renew able energy resources. In addition, the impact of disasters on the power system infrastructure is investigated and different types of optimization techniques that can be used to sustain the power flow in the network during disturbances are compared and analyzed. Furthermore, a comparative review analysis of different data-driven machine learning techniques for sustainable smart cities is performed along with the discussion on open research issues and challenges.